An ancient settlement with millennia of history and located on a strategic point along the Via Francigena, the village of Mignegno is clustered around its parish church, one of the oldest in the area. It is a village with a long history, as evidenced by the Church of the Assumption of Mary, which was already mentioned in a papal bill in 1187, indicating an origin that likely dates back even further.

The first houses in Mignegno were built around the square facing the church, a spot where today there are two bridges: one over the Magriola stream, still in use, while the remains of the other are found upstream from the Oratory of San Terenziano.

Inside the sacristy of the parish church in Mignegno, an image of the Madonna del Latte was discovered: this devotional image, dating back to the late 15th century, appears as a heavily damaged canvas and is no longer suitable for veneration by the faithful.

In addition to the parish church, the village of Mignegno has two other oratories: the Oratory of San Rocco, built after the plague epidemic of 1630, and the Oratory of San Terenziano, known for its devotion as well as the famous fair held annually on September 1. This oratory was built in the first half of the 16th century and expanded in the latter half of the 19th century, though it suffered significant damage in June 1884 due to the explosion at the nearby Bonzani powder mill.

Mignegno is also known for hosting an electromechanical nativity scene every year in the rectory of the Church of the Assumption of Mary. During the Christmas season, visitors can marvel at the nativity scene, with its numerous moving figurines, water features, and the enchanting transition from day to night, followed by the break of dawn.